Number of scholarships to award
- tuition fee reduction
A fully funded PhD position for 3 years is available starting in January 2024 within the School of Pharmacy, University of Kent. The aim is to investigate the mechanisms by which pain is regulated when hypertension and arthritis co-exist.
Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) leading to the use of many drugs (polypharmacy) to control a range of symptoms. Overmedication especially in the elderly is a considerable healthcare problem worldwide, increasing side effects and reducing quality of life. Arthritis (osteoarthritis [OA] and rheumatoid arthritis [RA]) is characterised by inflamed and damaged joints, leading to chronic pain and disability in the elderly. Hypertension is also highly prevalent in the ageing population. People with arthritis have an increased risk of developing hypertension. Interestingly, hypertension and arthritis share common disease pathways. Better understanding of these pathways could pave the way for (i) new targets for pain and (ii) more holistic management of both conditions.
The student will utilise a range of in-vitro, in-vivo and ex-vivo techniques to investigate the mechanisms by which pain is regulated when hypertension and arthritis co-exist. Arthritis will be induced (surgically/chemically) in spontaneously hypertensive rats and control rats to see if hypertension affects arthritis-induced pain and pathology.
Funding includes UKRI standard stipend, 100% of UK/home rate tuition fees and extra support for research training and research costs (£1,000 a year).
Open to Home students starting in January 2024.
To be classed as a "Home" student you must meet these UK residential conditions:
- Be a UK National (meeting UKRI residency requirements); or
- Have settled status; or
- Have pre-settled status (meeting residency requirement); or
- Have indefinite leave to remain or enter.
- Applicants should hold a minimum of upper-second class honours degree (or equivalent) in a relevant subject discipline, such as neuroscience, physiology, pathology, immunology or any other life sciences related subject area. Prior experience in inflammatory and immune mediated diseases or molecular biology and histopathology techniques will be an advantage, but not essential.
Study experience required
Closing date for all applicants is 31st October 2023 (23:59 GMT). Interviews will be held in November 2023 (options to have online or face-to-face interview).
Send your full CV and covering letter via email in the first instance and guidance will be provided on how to submit the formal application via the Kent Website.