Placeholder image for Genetics & Molecular Medicine (Research Division)

Genetics & Molecular Medicine (Research Division), Ph.D.

  • Application Deadline
  • 36 months
University rank #31 (QS) London, United Kingdom
The Department of Medical & Molecular Genetics was founded in 1960 as the Paediatric Research Unit, with an endowment from the Spastics Society (now Scope), in order to undertake developmental biology research relating to the origin of childhood handicaps such as cerebral palsy and spina bifida. The current Head of Department is Professor Tim Hubbard.
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The Department aims to identify the genes and genetic modifications which are implicated in a range of human diseases, including inflammatory bowel disease, psoriasis, systemic lupus erythematosus, birth defects, breast cancer and leukaemia.

Our progress in this research has been greatly facilitated by the acquisition of several high-throughput second-generation DNA sequencers by the King's College/Guy's and St Thomas' Biomedical Research Centre - these instruments can sequence all 20,000 genes in multiple patients in one week. 

Gene hunting in the Department is also supported by specialist expertise in mathematics and genetic epidemiology, which is required for studying inherited susceptibility to common, adult-onset diseases. Other work seeks to develop an understanding of epigenetic effects such as imprinting and control of gene expression, and to formulate novel analytical methodologies and methods of studying epistatic interactions between genes. 

Our research also encompasses Functional Genomics, which involves the application of new technologies in cell biology, molecular biology and biochemistry to study the molecular mechanisms of pathogenesis. 

Detailed Programme Facts

  • Programme intensity

    You can choose to do this programme part-time or full-time.

    • Full-time duration 36 months
    • Average part-time duration 48 months
    • Intensity Flexible
  • Languages
    • English
  • Delivery mode
    On Campus

Programme Structure

Programme structure:
  • The research strategy of the Department includes a strong commitment to apply the fruits of basic scientific discoveries to improved diagnosis and treatment for patients, in partnership with the adjacent NHS Genetics Centre and our comprehensive Biomedical Research Centre. 
  • In the progressive and fatal neurological disorder Huntington's disease, for example, we are screening large collections of chemical compounds for molecules that might delay or prevent the onset of this condition. 
  • In an acute form of leukaemia we have developed a molecular test that detects the recurrence of the cancer at a very early stage so that patients can be treated effectively, and we are screening tumours for the genetic changes that cause the cancer to progress. Such studies are likely to have a major impact on the future management of human disease.

English Language Requirements

This programme may require students to demonstrate proficiency in English.

Academic Requirements

You need the following GPA score:

Required score: Upper Second Class

Applicants for graduate programs must have the equivalent of a bachelor’s degree with a minimum GPA equivalent to Upper Second Class on the UK Honour scale. Admitted applicants typically have an undergraduate GPA of or better on the UK Honour scale. No exam grade should be lower than 4.5 (European grade scale) or D (American grade scale).

Your GPA (Grade Point Average) is calculated using the grades that you received in each course, and is determined by the points assigned to each grade (e.g. for the US grading scale from A-F).

General Requirements

  • Bachelor's degree with 2:1 honours (or overseas equivalent) in a relevant subject. A 2:2 degree may be considered only where applicants also offer a Masters degree with Merit or above.
  • Applicants are strongly advised to contact potential supervisors prior completing the online application form.

Tuition Fee

Living costs for London

  • 1137 - 2160 GBP/month
    Living Costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.


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