The Medical and Molecular Genetics Department at the King's College London aims to identify the genes and genetic modifications which are implicated in a range of human diseases, including inflammatory bowel disease, psoriasis, systemic lupus erythematosus, birth defects, breast cancer and leukaemia.
- Our progress in this research has been greatly facilitated by the acquisition of several high-throughput second-generation DNA sequencers by the King's College/Guy's and St Thomas' Biomedical Research Centre - these instruments can sequence all 20,000 genes in multiple patients in one week.
- Gene hunting in the Department is also supported by specialist expertise in mathematics and genetic epidemiology, which is required for studying inherited susceptibility to common, adult-onset diseases. Other work seeks to develop an understanding of epigenetic effects such as imprinting and control of gene expression, and to formulate novel analytical methodologies and methods of studying epistatic interactions between genes.
- Our research also encompasses Functional Genomics, which involves the application of new technologies in cell biology, molecular biology and biochemistry to study the molecular mechanisms of pathogenesis.
Programme StructureProgramme structure:
- The research strategy of the Department includes a strong commitment to apply the fruits of basic scientific discoveries to improved diagnosis and treatment for patients, in partnership with the adjacent NHS Genetics Centre and our comprehensive Biomedical Research Centre.
- In the progressive and fatal neurological disorder Huntington's disease, for example, we are screening large collections of chemical compounds for molecules that might delay or prevent the onset of this condition.
- In an acute form of leukaemia we have developed a molecular test that detects the recurrence of the cancer at a very early stage so that patients can be treated effectively, and we are screening tumours for the genetic changes that cause the cancer to progress. Such studies are likely to have a major impact on the future management of human disease.
We are not aware of any English requirements for this programme.
- Bachelor's degree with 2:1 honours (or overseas equivalent) in a relevant subject. A 2:2 degree may be considered only where applicants also offer a Masters degree with Merit or above.
- Applicants are strongly advised to contact potential supervisors prior completing the online application form.
Living costs for London
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.
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Apply and win up to €10000 to cover your tuition fees.
Updated in the last 9 months
Check the official programme website for potential updates.