Synaptic Micronetworks in Health and Disease University of Bonn

Overview

The overarching goal of the Synaptic Micronetworks in Health and Disease research group at the University of Bonn is to understand how behavior is generated by coordinated activity of neuronal circuits, and how this is disrupted in neurological disorders.

Key facts

The past decade has seen significant advances in this field, with the refinement of techniques for measuring and manipulating the activity of large populations of neurons in behaving animals, as well as the ability to quantify behavior in novel, extremely precise ways.

This has allowed to formulate and test new hypotheses about how neuronal activity represents features of the outside world, how neuronal circuits integrate environmental information with internal states, and how this leads to goal-directed behavior.