Structural Dynamics of GPCR Activation and Signaling, Ph.D. | Leipzig University | Leipzig, Germany
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Ph.D. On Campus

Structural Dynamics of GPCR Activation and Signaling

36 months
Duration
Free
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About

In the Collaborative Research Centre Structural Dynamics of GPCR Activation and Signaling at Leipzig University, scientists from the life sciences, medicine, pharmacy and bioinformatics of our university are investigating the interactions of GPCRs, the peptide receptors and the adhesion receptors

Overview

About the programme

The aim of this CRC Structural Dynamics of GPCR Activation and Signaling initiative at Leipzig University is to understand the structural dynamics of ligand binding, signal transduction, and downstream control of G protein- and arrestin-signaling pathways using native ligands as well as artificial probe molecules in conjunction with hybrid methods of structural biology including NMR, X-ray (conventional and serial protein X-ray crystallography at synchrotrons and free electron lasers), cryo-electron microscopy, mass spectrometry and computational methods (molecular modeling and dynamics).

Phenomena such as biased signaling are tackled using assays that target specific signaling pathways. Results are tied in with a phylogenetic analysis of GPCRs, arrestins and G proteins.  One goal of the CRC is to clarify the dynamic structural states of these GPCRs in order to understand their functions. This could lead to the development of novel therapeutics for this class of GPCRs.

Programme Structure

Research projects include:

  • Structural elucidation of neuropeptide GPCRs
  • Investigation of the structure and dynamics of the ghrelin/GHS receptor complex
  • Characterizing the molecular interactions of Y1 and Y2 receptors with NPY
  • Characterizing the molecular interaction between the Y receptor and arrestin
  • Structures of adhesion GPCR by cryo-electron microscopy
  • Enzymology of autoproteolysis and signaling function of the GAIN domain in adhesion GPCRs
  • Innovative Rosetta algorithms for comparative modeling and docking of GPCRs

Key information

Duration

  • Full-time
    • 36 months

Start dates & application deadlines

Language

English

Delivered

On Campus

Academic requirements

We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.

English requirements

We are not aware of any English requirements for this programme.

Student insurance

Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:

  • Additional medical costs (i.e. dental)
  • Repatriation, if something happens to you or your family
  • Liability
  • Home contents and baggage
  • Accidents
  • Legal aid

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Other requirements

General requirements

Required:

  • dated and signed application form
  • written confirmation from your supervisor (supervision agreement)
  • CV
  • secondary school leaving certificate (certified copy)
  • evidence of university entrance examination (certified copy), if applicable
  • evidence of all university degrees (certified copies), e.g. bachelor’s, master’s, Diplom)
  • Transcripts of Records from all secondary and university qualifications (certified copies)
  • evidence of your knowledge of German at DSH-2 level, if the doctorate will be in German (certified copy)
  • evidence of your knowledge of English, if the doctorate will be in English
  • confirmation of admission to a faculty’s list of doctoral candidates, if already available (confirmation can otherwise be submitted within one semester)

Tuition Fee

To always see correct tuition fees
  • International

    Free
    Tuition Fee
    Based on the tuition of 0 EUR per semester during 36 months.
  • EU/EEA

    Free
    Tuition Fee
    Based on the tuition of 0 EUR per semester during 36 months.
    • Students pay a semester fee (EUR 253,50)

Living costs for Leipzig

720 - 1047 EUR /month
Living costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

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Scholarships Information

Below you will find PhD's scholarship opportunities for Structural Dynamics of GPCR Activation and Signaling.

Available Scholarships

You are eligible to apply for these scholarships but a selection process will still be applied by the provider.

Independent provider
Grant
1300 EUR
Deadline
Not specified
Fully Funded DAAD EPOS Scholarship
Merit-based

Read more about eligibility

DAAD
Location not available
Independent provider
Grant
1200 EUR
Deadline
Not specified
Karl Schmidt Rottluff Scholarship
Merit-based

Read more about eligibility

Studienstiftung
Location not available
Independent provider
Grant
3500 USD
Deadline
15 Nov 2024
ACES Scholarships
Merit-based Need-based

Read more about eligibility

ACES Education Fund
Location not available
Independent provider
Grant
1300 EUR
Deadline
Not specified
Development-Related Postgraduate Courses (EPOS) • DAAD
Merit-based

Read more about eligibility

German Academic Exchange Service (DAAD)
Location not available
Independent provider
Grant
1200 EUR
Deadline
Not specified
Graduate School Scholarship Programme
Merit-based Need-based

Read more about eligibility

German Academic Exchange Service (DAAD)
Location not available
Independent provider
Grant
1000 USD
Deadline
30 Nov 2024
ServiceScape Scholarship
Merit-based Need-based

Read more about eligibility

ServiceScape
Location not available
Independent provider
Grant
Various benefits
Deadline
14 Oct 2024
Fulbright U.S. Student Program
Merit-based Need-based

Read more about eligibility

U.S. government
Location not available
Independent provider
Grant
649 EUR
Deadline
31 Dec 2024
Scholarship of the German National Academic Foundation
Merit-based

Read more about eligibility

Campus France
Location not available
Independent provider
Grant
1350 EUR
Deadline
31 Oct 2024
ELES-Scholarship (Ernst-Ludwig-Ehrlich-Studienwerk)
Merit-based Need-based

Read more about eligibility

Austria’s Agency for Education and Internationalisation
Location not available
Independent provider
Grant
Various benefits
Deadline
31 Dec 2024
Grants of the Leopold Figl Foundation for students with residence in Lower Austria
Need-based

Read more about eligibility

Leopold Figl Foundation
Location not available
Independent provider
Grant
Various benefits
Deadline
Not specified
Erasmus+ - Grants for study mobility
Merit-based

Read more about eligibility

OeAD, Austria's Agency for Education and Internationalisation
Location not available
Independent provider
Grant
5000 USD
Deadline
25 Aug 2024
Women Scholarship for International Students
Merit-based

Read more about eligibility

educations.com
Location not available
Independent provider
Grant
90000 AUD
Deadline
Not specified
World Universities Ramsay Postgraduate Scholarship
Merit-based Need-based

Read more about eligibility

The Ramsay Centre
Location not available
Independent provider
Grant
3000 USD
Deadline
31 Dec 2025
Scholarship for students with disabilities
Need-based

Read more about eligibility

Anonymous Hope Fund
Location not available
Independent provider
Grant
12000 USD
Deadline
30 Nov 2024
Tobacco Harm Reduction Scholarship Programme
Merit-based Need-based

Read more about eligibility

The Tobacco Harm Reduction Scholarship Programme
Location not available
Independent provider
Grant
3000 USD
Deadline
Not specified
AAPG Foundation Grants-in-Aid
Merit-based Need-based

Read more about eligibility

American Association of Petroleum Geologists Foundation
Location not available
Independent provider
Grant
1000 USD
Deadline
31 Oct 2024
$1,500 Annual Video Contest Scholarship
Merit-based

Read more about eligibility

IvyPanda
Location not available

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