Studyportals
Ph.D. On Campus

Structural Dynamics of GPCR Activation and Signaling Leipzig University

36 months
Duration
Free
Free
Unknown
Anytime
Unknown
Apply date
Unknown
Start date

About

In the Collaborative Research Centre Structural Dynamics of GPCR Activation and Signaling at Leipzig University, scientists from the life sciences, medicine, pharmacy and bioinformatics of our university are investigating the interactions of GPCRs, the peptide receptors and the adhesion receptors

Overview

About the programme

The aim of this CRC Structural Dynamics of GPCR Activation and Signaling initiative at Leipzig University is to understand the structural dynamics of ligand binding, signal transduction, and downstream control of G protein- and arrestin-signaling pathways using native ligands as well as artificial probe molecules in conjunction with hybrid methods of structural biology including NMR, X-ray (conventional and serial protein X-ray crystallography at synchrotrons and free electron lasers), cryo-electron microscopy, mass spectrometry and computational methods (molecular modeling and dynamics).

Phenomena such as biased signaling are tackled using assays that target specific signaling pathways. Results are tied in with a phylogenetic analysis of GPCRs, arrestins and G proteins.  One goal of the CRC is to clarify the dynamic structural states of these GPCRs in order to understand their functions. This could lead to the development of novel therapeutics for this class of GPCRs.

Programme Structure

Research projects include:

  • Structural elucidation of neuropeptide GPCRs
  • Investigation of the structure and dynamics of the ghrelin/GHS receptor complex
  • Characterizing the molecular interactions of Y1 and Y2 receptors with NPY
  • Characterizing the molecular interaction between the Y receptor and arrestin
  • Structures of adhesion GPCR by cryo-electron microscopy
  • Enzymology of autoproteolysis and signaling function of the GAIN domain in adhesion GPCRs
  • Innovative Rosetta algorithms for comparative modeling and docking of GPCRs

Key information

Duration

  • Full-time
    • 36 months

Start dates & application deadlines

Language

English

Delivered

On Campus

What students do after studying

Join for free or log in to access our complete career info list.

Academic requirements

We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.

English requirements

We are not aware of any English requirements for this programme.

Student insurance

Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:

  • Additional medical costs (i.e. dental)
  • Repatriation, if something happens to you or your family
  • Liability
  • Home contents and baggage
  • Accidents
  • Legal aid

We partnered with Aon to provide you with the best affordable student insurance, for a carefree experience away from home.

Get your student insurance now

Starting from €0.53/day, free cancellation any time.

Remember, countries and universities may have specific insurance requirements. To learn more about how student insurance work at Leipzig University and/or in Germany, please visit Student Insurance Portal.

Other requirements

General requirements

Required:

  • dated and signed application form
  • written confirmation from your supervisor (supervision agreement)
  • CV
  • secondary school leaving certificate (certified copy)
  • evidence of university entrance examination (certified copy), if applicable
  • evidence of all university degrees (certified copies), e.g. bachelor’s, master’s, Diplom)
  • Transcripts of Records from all secondary and university qualifications (certified copies)
  • evidence of your knowledge of German at DSH-2 level, if the doctorate will be in German (certified copy)
  • evidence of your knowledge of English, if the doctorate will be in English
  • confirmation of admission to a faculty’s list of doctoral candidates, if already available (confirmation can otherwise be submitted within one semester)

Tuition Fee

To always see correct tuition fees
  • International

    Free
    Tuition Fee
    Based on the tuition of 0 EUR per semester during 36 months.
  • EU/EEA

    Free
    Tuition Fee
    Based on the tuition of 0 EUR per semester during 36 months.
    • Students pay a semester fee (EUR 253,50)

Living costs for Leipzig

720 - 1047 EUR /month
Living costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

In order for us to give you accurate scholarship information, we ask that you please confirm a few details and create an account with us.

Loading

Scholarships Information

Below you will find PhD's scholarship opportunities for Structural Dynamics of GPCR Activation and Signaling.

Available Scholarships

You are eligible to apply for these scholarships but a selection process will still be applied by the provider.

Independent provider
Grant
1300 EUR
Deadline
Not specified
Fully Funded DAAD EPOS Scholarship
Merit-based

Read more about eligibility

DAAD
Location not available
Independent provider
Grant
1200 EUR
Deadline
Not specified
Karl Schmidt Rottluff Scholarship
Merit-based

Read more about eligibility

Studienstiftung
Location not available
Independent provider
Grant
1300 EUR
Deadline
Not specified
Development-Related Postgraduate Courses (EPOS) • DAAD
Merit-based

Read more about eligibility

German Academic Exchange Service (DAAD)
Location not available
Independent provider
Grant
1200 EUR
Deadline
Not specified
Graduate School Scholarship Programme
Merit-based Need-based

Read more about eligibility

German Academic Exchange Service (DAAD)
Location not available
Independent provider
Grant
Various benefits
Deadline
Not specified
Erasmus+ - Grants for study mobility
Merit-based

Read more about eligibility

OeAD, Austria's Agency for Education and Internationalisation
Location not available
Independent provider
Grant
10000 USD
Deadline
01 Sep 2025
The PhD Prep Fellowship
Merit-based

Read more about eligibility

Admit Lab
Location not available
Independent provider
Grant
1000 USD
Deadline
09 Jul 2025
Dream Chaser Scholarship
Merit-based

Read more about eligibility

Salvado Law
Location not available
Independent provider
Grant
90000 AUD
Deadline
Not specified
World Universities Ramsay Postgraduate Scholarship
Merit-based Need-based

Read more about eligibility

The Ramsay Centre
Location not available
Independent provider
Grant
3000 USD
Deadline
31 Dec 2025
Scholarship for students with disabilities
Need-based

Read more about eligibility

Anonymous Hope Fund
Location not available
Independent provider
Grant
3000 USD
Deadline
Not specified
AAPG Foundation Grants-in-Aid
Merit-based Need-based

Read more about eligibility

American Association of Petroleum Geologists Foundation
Location not available
Independent provider
Grant
1000 USD
Deadline
20 May 2025
PlagiarismSearch 2025 Essay Contest
Merit-based

Read more about eligibility

PlagiarismSearch
Location not available
Independent provider
Grant
1000 USD
Deadline
01 Mar 2025
Voice Talent Online Scholarship
Merit-based Need-based

Read more about eligibility

Voice Talent Online
Location not available

Other interesting programmes for you

Our partners

Structural Dynamics of GPCR Activation and Signaling
Leipzig University
Structural Dynamics of GPCR Activation and Signaling
-
Leipzig University

Wishlist

Go to your profile page to get personalised recommendations!