Overview

About the program

Unraveling molecular resistance mechanisms against pharmacologically active compounds as well as the search for new bioactive compounds that can overcome either intrinsic or extrinsic resistance are core subjects of pharmaceutical research.

This important topic will be investigated within the Natural Products and Natural Product Analogs Against Therapy-Resistant Tumors and Microorganisms Research Training Group at Heinrich Heine University Düsseldorf as exemplified by chemoresistant tumors and infections with chemoresistant microbial pathogens.

Both forms of diseases are characterized by numerous resistance mechanisms against currently available drugs which may either weaken the success of drug therapy or which will render it completely ineffective.

Programme Structure

Scientific projects include:

Characterization and optimization of apoptosis- and autophagy-modulating natural products and derivatives for the elimination of therapy-resistant tumor cells
Natural product/HDAC inhibitor-mediated modulation of immune responses and cytostatic-induced stress responses for resensitization of therapy-resistant tumors
Characterization of the mechanism of action and medicinal chemistry optimization of antimicrobial natural products
Nisin as a model system for overcoming lantibiotic resistance in bacterial pathogens

Key information

Duration

Full-time
- 36 months

Start dates & application deadlines

Starting 2025-10-01 00:00:00

Application deadline not specified.

Language

English

TOEFL^® IBT

80

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Delivered

On Campus

Disciplines

Biology Medicine View 26 other PhDs in Medicine in Germany

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Academic requirements

We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.

English requirements

TOEFL^® IBT

80

Schedule TOEFL®

Student insurance

Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:

Additional medical costs (i.e. dental)
Repatriation, if something happens to you or your family
Liability
Home contents and baggage
Accidents
Legal aid

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Other requirements

General requirements

Normally you need to hold an excellent master's or diploma degree in the appropriate field.
A good command of either English or German is a requirement for acceptance.

Tuition Fee

To always see correct tuition fees

International

Free

Tuition Fee

Based on the tuition of 0 EUR per year during 36 months.
EU/EEA

Free

Tuition Fee

Based on the tuition of 0 EUR per year during 36 months.

social contribution fee: €321 per semester

Living costs for Düsseldorf

996 - 1318 EUR /month

Living costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

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Scholarships Information

Below you will find PhD's scholarship opportunities for Natural Products and Natural Product Analogs Against Therapy-Resistant Tumors and Microorganisms.