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Biomedicine, PhD, MD

  • Application Deadline
  • 36 months
    Duration
University rank #152 (QS) Newcastle upon Tyne, United Kingdom
We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.
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Overview

As a student in Biomedicine you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.

Quality and Ranking

We rank in the top 100 for Medicine - QS World University Rankings by Subject 2019.

Areas of research

We undertake the following areas of research and offer MPhil, PhD and MD supervision in:

Applied immunobiology (including organ and haematogenous stem cell transplantation)

Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are currently investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We also have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. A further research theme is focusses on primary immunodeficiency diseases.

Find out more about applied immunobiology research, projects and staff specialisms.

Dermatology

There is a strong emphasis on the integration of clinical investigation with basic science. Our research themes include:

  • cell signalling in normal and diseased skin including mechanotransduction and response to ultraviolet radiation
  • dermatopharmacology including mechanisms of psoriatic plaque resolution in response to therapy
  • stem cell biology and gene therapy
  • regulation of apoptosis/autophagy
  • non-melanoma skin cancer/melanoma biology and therapy.

We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.

Find out more about dermatology research, projects and staff specialisms.

Diabetes

This area places emphasis on translational research, linking clinical- and laboratory-based science. Our key research themes include:

  • mechanisms of insulin action and glucose homeostasis
  • insulin secretion and pancreatic beta-cell function
  • diabetic complications
  • stem cell therapies
  • genetics and epidemiology of diabetes.

Find out more about diabetes research, projects and staff specialisms.

Diagnostic and therapeutic technologies

Our focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:

  • bacterial infection
  • chronic liver failure
  • cardiovascular and degenerative diseases.

This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.

Find out more about diagnostic and therapeutic technologies research, projects and staff specialisms.

Kidney disease

There are a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas of interest include:

  • haemolytic uraemic syndrome
  • renal inflammation and fibrosis
  • the immunology of transplant rejection
  • tubular disease
  • cystic kidney disease.
The liver

We have particular interests in:

  • primary biliary cirrhosis (epidemiology, immunobiology and genetics)
  • alcoholic and non-alcoholic fatty liver disease
  • fibrosis
  • the genetics of other autoimmune and viral liver diseases.
Magnetic Resonance (MR), spectroscopy and imaging in clinical research

Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:

  • MR physics projects involve development and testing of new MR techniques that make quantitative measurements of physiological properties using a safe, repeatable MR scan.
  • Clinical research projects involve the application of these novel biomarkers to investigation of human health and disease.

Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.

Find out more about Magnetic Resonance (MR), spectroscopy and imaging in clinical research, projects and staff specialisms.

Musculoskeletal disease (including auto-immune arthritis)

We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:

  • what causes the destruction of joints (cell signalling, injury and repair)
  • how cells in the joints respond when tissue is lost (cellular interactions)
  • whether we can alter the immune system and ‘switch off’ auto-immune disease (targeted therapies and diagnostics).

This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.

Find out more about musculoskeletal disease (including autoimmune arthritis) research, projects and staff specialisms.

Pharmacogenomics (including complex disease genetics)

Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.

Find out more about pharmacogenomics (including complex disease genetics) research, projects and staff specialisms.

Reproductive and vascular biology

Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:

  • the regulation of trophoblast and uNk cells
  • transcriptional and post-translational features of uterine function
  • cardiac and vascular remodelling in pregnancy

We also have preclinical molecular biology projects in breast cancer research.

Find out more about reproductive and vascular biology research, projects and staff specialisms.

Respiratory disease

We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:

  • acute lung injury - lung infections
  • chronic obstructive pulmonary disease
  • fibrotic disease of the lung, both before and after lung transplantation.

Find out more about respiratory disease research, projects and staff specialisms.

Pharmacology, Toxicology and Therapeutics

Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.

Find out more about pharmacology, toxicology and therapeutics research, projects and staff specialisms.

Joint doctoral PhD degree programme in biomedical sciences

Newcastle University offers a joint doctoral PhD degree programme in biomedical sciences with the Faculty of Medicine, Universitas Indonesia (FKUI).

You spend at least one year of your studies in each university and are jointly supervised by staff from Newcastle University and Universitas Indonesia. This leads to a single award from both institutions. The development of the Joint Doctoral PhD programme has been generously supported under the Prime Minister's Initiative 2 Programme and the British Council Indonesia.

Further information on this joint doctoral research programme

Faculty of Medical SciencesTelephone: +44 (0) 191 208 4841 Email: biomed-international-pg@ncl.ac.uk

Detailed Programme Facts

  • Deadline and start date

    There is no application closing date but specific deadlines for funding may apply. We suggest international students apply at least two months beforehand.

  • Programme intensity

    You can choose to do this programme part-time or full-time.

    Full-time
    • Full-time duration 36 months
    Part-time
    • Average part-time duration 72 months
  • Languages
    • English
  • Delivery mode
    On Campus

Programme Structure

See Modules tab in the Programme information in our online Prospectus.

English Language Requirements

You need the following IELTS score:

  • Minimum required score:

    6.5

    The IELTS – or the International English Language Test System – tests your English-language abilities (writing, listening, speaking, and reading) on a scale of 1.00–9.00. The minimum IELTS score requirement refers to which Overall Band Score you received, which is your combined average score. Read more about IELTS.

Academic Requirements

You need the following GPA score:

Required score: Upper Second Class

Applicants for graduate programs must have the equivalent of a bachelor’s degree with a minimum GPA equivalent to Upper Second Class on the UK Honour scale. Admitted applicants typically have an undergraduate GPA of or better on the UK Honour scale. No exam grade should be lower than 4.5 (European grade scale) or D (American grade scale).

Your GPA (Grade Point Average) is calculated using the grades that you received in each course, and is determined by the points assigned to each grade (e.g. for the US grading scale from A-F).

General Requirements

PhD

  • A 2:1 honours degree, or international equivalent. Further research experience or a master’s degree would be advantageous.
MD
  • A MBBS, or an equivalent medical degree.

Tuition Fee

MPhil, PhD, MDUK & EU

Full time: £4,327 - 15,127Part time: £2,164 - £7,564

International

Full time: £22,110 - £32,910.

Living costs for Newcastle upon Tyne

  • 560 - 1000 GBP/month
    Living Costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

See Fees and Funding tab in the Programme information in our online Prospectus.

Studyportals Tip: Students can search online for independent or external scholarships that can help fund their studies. Check the scholarships to see whether you are eligible to apply. Many scholarships are either merit-based or needs-based.

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