Overview
Context of Is there a role for Fusobacterium nucelatum, candida or HV16 in oral disease progression study at University of Dundee
The prognostic impact of would be investigated.
Oral squamous cell carcinoma (OSCC) accounts for over 90% of all oral cancers and is generally considered the 8th most common cancer worldwide [1]. Despite therapeutic advances, the 5-year survival rate is approximately 50%, making OSCC one of the most devastating malignancies [1]. Recognised risk factors for OSCC include tobacco and alcohol consumption [1]. However, many patients develop OSCC who lack these risk factors leading to speculation about the role of the oral microbiome in the development of OSCC.
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- Inflammation caused by infections has been suggested to be one of the most important preventable causes of cancers in general
- Fusobacterium nucleatum is a commensal of the human oral cavity which is associated with subgingival plaque and poor oral hygiene and has been implicated as a driver of the progression of colorectal carcinoma
- Yeasts, such as Candida, may invade oral epithelium and may also be causally involved in dysplastic changes.
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Duration
- Full-time
- 36 months
Start dates & application deadlines
- StartingApplication deadline not specified.
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Medicine Dentistry Health Sciences View 243 other PhDs in Health Sciences in United KingdomExplore more key information
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General requirements
- You should have an honours degree at 2.1 or above, and/or a Masters degree in a relevant discipline.
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International
25410 GBP/yearTuition FeeBased on the tuition of 25410 GBP per year during 36 months. -
National
4825 GBP/yearTuition FeeBased on the tuition of 4825 GBP per year during 36 months.
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