Overview
Techniques:
The student from Targeting Ras palmitoylation for the treatment of cancer at University of Dundee will gain experience of mammalian cell culture, molecular biology techniques (including PCR and site-directed mutagenesis), pharmacology, acyl-RAC (assay for determining protein palmitoylation levels), co-immunoprecipitation and pulldown experiments, SDS-PAGE and Western blotting, protein expression (bacteria, yeast) and purification as well as Hydrogen-Deuterium Exchange (HDX) mass spectrometry.
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Visit programme websiteProgramme Structure
- Scientific summary: In humans, the genes HRAS, NRAS and KRAS encode three closely related proteins frequently mutated in cancer promoting unregulated cell growth.
- Ras proteins function as molecular switches transmitting signals from cell surface growth factor receptors to intracellular effector proteins cycling between inactive (GDP bound) and active (GTP) states.
- Oncogenic Ras activity requires the protein to be localised to the inner face of the plasma membrane suggesting strategies that cause Ras to be mistargeted within the cell may be effective in treating cancer.
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Visit programme websiteKey information
Duration
- Full-time
- 36 months
- Part-time
- 60 months
Start dates & application deadlines
- StartingApplication deadline not specified.
- Starting
- Apply before
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Language
Delivered
Disciplines
Molecular Sciences Health Sciences View 32 other PhDs in Molecular Sciences in United KingdomExplore more key information
Visit programme websiteAcademic requirements
English requirements
We are not aware of any English requirements for this programme.
Student insurance
Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:
- Additional medical costs (i.e. dental)
- Repatriation, if something happens to you or your family
- Liability
- Home contents and baggage
- Accidents
- Legal aid
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Other requirements
General requirements
You should have an honours degree at 2.1 or above, and/or a Masters degree in a relevant discipline.
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Visit programme websiteTuition Fee
-
International
20895 GBP/yearTuition FeeBased on the tuition of 20895 GBP per year during 36 months. -
National
4825 GBP/yearTuition FeeBased on the tuition of 4825 GBP per year during 36 months.
Living costs for Dundee
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.
Funding
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Scholarships Information
Below you will find PhD's scholarship opportunities for Targeting Ras palmitoylation for the treatment of cancer.
Available Scholarships
You are eligible to apply for these scholarships but a selection process will still be applied by the provider.
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