Overview

Techniques:

The student from Targeting Ras palmitoylation for the treatment of cancer at University of Dundee will gain experience of mammalian cell culture, molecular biology techniques (including PCR and site-directed mutagenesis), pharmacology, acyl-RAC (assay for determining protein palmitoylation levels), co-immunoprecipitation and pulldown experiments, SDS-PAGE and Western blotting, protein expression (bacteria, yeast) and purification as well as Hydrogen-Deuterium Exchange (HDX) mass spectrometry.

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Programme Structure

Programme include:

Scientific summary: In humans, the genes HRAS, NRAS and KRAS encode three closely related proteins frequently mutated in cancer promoting unregulated cell growth.

Ras proteins function as molecular switches transmitting signals from cell surface growth factor receptors to intracellular effector proteins cycling between inactive (GDP bound) and active (GTP) states.
Oncogenic Ras activity requires the protein to be localised to the inner face of the plasma membrane suggesting strategies that cause Ras to be mistargeted within the cell may be effective in treating cancer.

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Key information

Duration

Full-time
- 36 months
Part-time
- 60 months

Start dates & application deadlines

Starting 2027-01-12 00:00:00
- Apply before 2026-10-31 00:00:00

Language

English

IELTS

6.5

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4.9/5 student rating

Delivered

On Campus

Campus Location

Dundee, United Kingdom

Disciplines

Molecular Sciences Health Sciences View 36 other PhDs in Molecular Sciences in United Kingdom

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Academic requirements

GPA

Upper Second Class

English requirements

IELTS

6.5

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Other requirements

General requirements

You should have an honours degree at 2.1 or above, and/or a Masters degree in a relevant discipline.

IELTS 6.5

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Tuition Fees

Tuition fees are shown in and the most likely applicable fee is shown based on your nationality.

International Applies to you

Applies to you

Non-residents

21940 GBP / year

≈ 21940 GBP / year
Domestic Applies to you

Applies to you

Citizens or residents

5006 GBP / year

≈ 5006 GBP / year

Living costs

Dundee

United Kingdom

787 - 1494 GBP / month

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

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Scholarships Information

Below you will find PhD's scholarship opportunities for Targeting Ras palmitoylation for the treatment of cancer.

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About

Overview

Techniques:

Get more details

Programme Structure

Check out the full curriculum

Key information

Duration

Start dates & application deadlines

Language

Prepare for Your English Test

Delivered

Campus Location

Disciplines

Explore more key information

What students do after studying

Academic requirements

English requirements

Prepare for Your English Test

Other requirements

General requirements

Make sure you meet all requirements

Tuition Fees

International Applies to you

Domestic Applies to you

Living costs

Dundee

Funding

Check for any work restrictions

Scholarships Information

Available Scholarships

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