Overview

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Remarkably, senescent cells that originated from a G1 or G2 arrested have never previously been compared, even though these states are very different.

One goal of this Investigating how dormant senescent cells can drive drug-resistance following chemotherapy project at University of Dundee will be to characterise these different states using mass-spec proteomics and RNA sequencing.

Diversity statement

Our research community thrives on the diversity of students and staff which helps to make the University of Dundee a UK university of choice for postgraduate research. We welcome applications from all talented individuals and are committed to widening access to those who have the ability and potential to benefit from higher education.

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Programme Structure

The second goal of the studentship is to test this hypothesis by

characterising cell cycle re-entry in senescent cells using a range of fixed and live cell microscopy techniques, before linking any defects to chromosomal instability, tumour evolution and drug resistance.

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Key information

Duration

Full-time
- 36 months
Part-time
- 60 months

Start dates & application deadlines

Starting 2025-05-01 00:00:00

Application deadline not specified.
Starting 2025-09-16 00:00:00

Application deadline not specified.
Starting 2026-01-13 00:00:00
- Apply before 2025-10-31 00:00:00

Language

English

Delivered

On Campus

Disciplines

Medicine View 248 other PhDs in Medicine in United Kingdom

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Academic requirements

GPA

Upper Second Class

English requirements

We are not aware of any English requirements for this programme.

Student insurance

Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:

Additional medical costs (i.e. dental)
Repatriation, if something happens to you or your family
Liability
Home contents and baggage
Accidents
Legal aid

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Other requirements

General requirements

You should have an honours degree at 2.1 or above, and/or a Masters degree in a relevant discipline.

IELTS 6.5

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Tuition Fee

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International

21940 GBP/year

Tuition Fee

Based on the tuition of 21940 GBP per year during 36 months.
National

4786 GBP/year

Tuition Fee

Based on the tuition of 4786 GBP per year during 36 months.

Band 2

National: £9,120

International: £26,570

Band 3

National: £13,148

International: £30,965 or £39,800

Living costs for Dundee

787 - 1494 GBP /month

Living costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.