Overview

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Remarkably, senescent cells that originated from a G1 or G2 arrested have never previously been compared, even though these states are very different.

One goal of this Investigating how dormant senescent cells can drive drug-resistance following chemotherapy project at University of Dundee will be to characterise these different states using mass-spec proteomics and RNA sequencing.

Diversity statement

Our research community thrives on the diversity of students and staff which helps to make the University of Dundee a UK university of choice for postgraduate research. We welcome applications from all talented individuals and are committed to widening access to those who have the ability and potential to benefit from higher education.

Programme Structure

The second goal of the studentship is to test this hypothesis by

characterising cell cycle re-entry in senescent cells using a range of fixed and live cell microscopy techniques, before linking any defects to chromosomal instability, tumour evolution and drug resistance.

Key information

Duration

Full-time
- 36 months
Part-time
- 60 months

Start dates & application deadlines

Starting 2026-09-16 00:00:00

Application deadline not specified.
Starting 2027-01-13 00:00:00
- Apply before 2026-10-31 00:00:00
Starting 2027-05-01 00:00:00

Application deadline not specified.

Language

English

Delivered

On Campus

Campus Location

Dundee, United Kingdom

Disciplines

Medicine View 219 other PhDs in Medicine in United Kingdom

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Academic requirements

GPA

Upper Second Class

English requirements

We are not aware of any English requirements for this programme.

Other requirements

General requirements

You should have an honours degree at 2.1 or above, and/or a Masters degree in a relevant discipline.

IELTS 6.5

Tuition Fees

Tuition fees are shown in and the most likely applicable fee is shown based on your nationality.

International Applies to you

Applies to you

Non-residents

21940 GBP / year

≈ 21940 GBP / year
Domestic Applies to you

Applies to you

Citizens or residents

4786 GBP / year

≈ 4786 GBP / year

Additional Details

Band 2

National: £9,120

International: £26,570

Band 3

National: £13,148

International: £30,965 or £39,800

Living costs

Dundee

United Kingdom

787 - 1494 GBP / month

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

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Scholarships Information

Below you will find PhD's scholarship opportunities for Investigating how dormant senescent cells can drive drug-resistance following chemotherapy.

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