Overview
Context of Combining laser and ultrasound based molecular delivery strategies for enhanced drug delivery at University of Dundee
If successful, the approach will have direct and positive consequences for the treatment of a range of skin diseases, but may also be viewed as a more generic means of drug delivery for treating a much wider range of diseases.
Given the poor oral bioavailability of many pharmaceuticals, including nucleic acids, the skin represents an attractive target organ for delivery, bypassing the liver, and offering complete accessibility.
The main challenge is to achieve efficient and painless passage across the otherwise impenetrable stratum corneum (SC) and subsequently affect dispersal and uptake into the viable cells below. No single system is available at present that achieves this in a reliable way: iontophoresis, electroporation, microneedles, ultrasound, photomechanical effects and superficial laser ablation have been tried with varying success. We are unique in advocating a hybrid approach.
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Visit programme websiteProgramme Structure
- Physics driven drug delivery
- We intend to assess, develop, and optimise ablative fractional resurfacing (AFR) of skin, in order to achieve drug delivery of our target therapeutics. AFR is a novel laser procedure that has recently received favourable reviews for its efficacy and safety in aesthetic contexts.
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Visit programme websiteKey information
Duration
- Full-time
- 36 months
Start dates & application deadlines
- StartingApplication deadline not specified.
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Language
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Disciplines
Industrial & Systems Engineering General Engineering & Technology Nuclear Engineering View 117 other PhDs in General Engineering & Technology in United KingdomExplore more key information
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English requirements
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Other requirements
General requirements
- You should have an honours degree at 2.1 or above, and/or a Masters degree in a relevant discipline.
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Visit programme websiteTuition Fee
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International
25305 GBP/yearTuition FeeBased on the tuition of 25305 GBP per year during 36 months. -
National
4825 GBP/yearTuition FeeBased on the tuition of 4825 GBP per year during 36 months.
Living costs for Dundee
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.
Funding
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Scholarships Information
Below you will find PhD's scholarship opportunities for Combining laser and ultrasound based molecular delivery strategies for enhanced drug delivery.
Available Scholarships
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