Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation, Ph.D. | University of Dundee | Dundee, United Kingdom
36 months
Duration
25200 GBP/year
4825 GBP/year
Unknown
Unknown
Unknown
Apply date
Unknown
Start date

About

The aim of Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation at the University of Dundee now to identify natural interactors or substrates of these E3 ligases by interaction studies and narrow down the shortest part of the interacting proteins needed for this interaction.

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Overview

Context of Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation at University of Dundee

Therefore, the development of PROTACs is a rapidly growing area of research. Additionally, not every E3 ligase can target every protein recruited via PROTACs for degradation, and there have been reports of cancer cells developing a resistance to PROTACs via mutations in E3 ligases. Therefore, the expansion of the PROTAC toolbox by identification and inclusion of novel E3 ligase recruiting molecules is an important and critical step in targeted protein degradation.

Programme Structure

  • With this project, we seek to identify short protein sequences (peptides) capable of recruiting E3 ligases, determine the molecular mechanisms of the interactions and exploit the findings for potential use in novel PROTAC development. 
  • We have already analysed several novel E3 ligases for their ability to degrade different target proteins and have found a set of four E3 ligases which can efficiently target proteins in different subcellular locations.

Key information

Duration

  • Full-time
    • 36 months

Start dates & application deadlines

Language

English
TOEFL admission requirements TOEFL® IBT
87

Delivered

On Campus

Academic requirements

GPA admission requirements GPA
Upper Second Class

English requirements

TOEFL admission requirements TOEFL® IBT
87

Other requirements

General requirements

  • Send a copy of your CV
  • Discuss your potential application and any practicalities (e.g. suitable start date).

Tuition Fee

To always see correct tuition fees
  • International

    25200 GBP/year
    Tuition Fee
    Based on the tuition of 25200 GBP per year during 36 months.
  • National

    4825 GBP/year
    Tuition Fee
    Based on the tuition of 4825 GBP per year during 36 months.

Living costs for Dundee

787 - 1494 GBP /month
Living costs

The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.

Funding

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Scholarships Information

Below you will find PhD's scholarship opportunities for Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation.

Available Scholarships

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Provided by university
Grant
4000 GBP
Deadline
08 Jan 2025
Vice Chancellor's South Asia scholarship
Merit-based Need-based

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University of Dundee
Dundee, United Kingdom
Provided by university
Grant
20000 GBP
Deadline
16 Sep 2024
Vice Chancellor's South Asia Scholarship (September 2024)
Merit-based Need-based

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University of Dundee
Dundee, United Kingdom
Provided by university
Grant
5000 GBP
Deadline
08 Jan 2025
Vice Chancellor's Africa scholarship (January 2025)
Merit-based

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University of Dundee
Dundee, United Kingdom
Provided by university
Grant
6000 GBP
Deadline
08 Jan 2025
Global Excellence Scholarship (January)
Merit-based

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University of Dundee
Dundee, United Kingdom
Provided by university
Grant
5000 GBP
Deadline
08 Jan 2025
Global Citizenship Scholarship
Merit-based

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University of Dundee
Dundee, United Kingdom
Provided by university
Grant
3000 GBP
Deadline
10 Jan 2025
Alumni Scholarship
Merit-based

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University of Dundee
Dundee, United Kingdom
Independent provider
Grant
50000 INR
Deadline
31 Mar 2024
UniCreds Fly High Scholarship
Merit-based

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Unicreds
Location not available
Independent provider
Grant
Various benefits
Deadline
30 Mar 2024
Aga Khan Foundation International Scholarship Programme
Merit-based

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Aga Khan Foundation
Location not available
Independent provider
Grant
Various benefits
Deadline
Not specified
Full Support for Tuition and Costs of Living- PhD Scholarship at the University of Essex
Merit-based

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Junhua Li
Location not available
Independent provider
Grant
10000 GBP
Deadline
10 Jun 2024
GREAT Scholarship
Merit-based

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British Council - Accreditation UK
Location not available
Independent provider
Grant
3500 USD
Deadline
15 Nov 2024
ACES Scholarships
Merit-based Need-based

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ACES Education Fund
Location not available
Independent provider
Grant
1652 GBP
Deadline
Not specified
Commonwealth Shared Scholarship – University Bids
Merit-based Need-based

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UK Foreign, Commonwealth and Development Office (FCDO)
Location not available
Independent provider
Grant
Various benefits
Deadline
14 Oct 2024
Fulbright U.S. Student Program
Merit-based Need-based

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U.S. government
Location not available
Independent provider
Grant
1600 USD
Deadline
30 Apr 2024
Mozida African Master Scholarship
Merit-based

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Mozida Foundation
Location not available
Independent provider
Grant
90000 AUD
Deadline
Not specified
World Universities Ramsay Postgraduate Scholarship
Merit-based Need-based

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The Ramsay Centre
Location not available
Independent provider
Grant
3000 USD
Deadline
31 Dec 2025
Scholarship for students with disabilities
Need-based

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Anonymous Hope Fund
Location not available
Independent provider
Grant
12000 USD
Deadline
30 Nov 2024
Tobacco Harm Reduction Scholarship Programme
Merit-based Need-based

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The Tobacco Harm Reduction Scholarship Programme
Location not available
Independent provider
Grant
1500 USD
Deadline
15 May 2024
iVisa Annual Scholarship
Merit-based

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iVisa
Location not available
Independent provider
Grant
1500 USD
Deadline
31 Mar 2024
The Annual IELTS from 6 to 9 Scholarship
Merit-based Need-based

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IELTS from 6 to 9
Location not available
Independent provider
Grant
1000 USD
Deadline
30 Jun 2024
$1,500 Annual Essay Writing Contest Scholarship
Merit-based Need-based

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IvyPanda
Location not available
Independent provider
Grant
3000 USD
Deadline
Not specified
AAPG Foundation Grants-in-Aid
Merit-based Need-based

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American Association of Petroleum Geologists Foundation
Location not available
Independent provider
Grant
3000 USD
Deadline
Not specified
Anonymous Hope Fund
Merit-based Need-based

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Anonymous Hope Fund
Location not available
Independent provider
Grant
500 USD
Deadline
30 Apr 2024
Biotin Xtreme Hair Care Annual Scholarship 2023: Empowering The Future Of Hair Care
General Scholarships

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Biotin Xtreme Hair Care
Location not available

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation
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